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. 2021 Aug 31;32(2):1320–1329. doi: 10.1007/s00330-021-08218-9

Table 3.

Univariate and multivariate analysis of the correlation between LSR and clinical laboratory parameters

Parameter Univariate analysis Multivariate analysis (n = 335)
Spearman’s rho p value Estimate Standard error p value
Albumin 0.193 < 0.001 0.010 0.004 0.022
Bilirubin −0.215 < 0.001 −0.006 0.003 0.045
INR −0.030 0.584
ALT −0.063 0.228
AST −0.191 < 0.001 −0.053 0.024 0.031
GGT −0.038 0.472
ALP −0.085 0.108
Total protein −0.056 0.297
Platelet count 0.148 0.004 0.0007 0.0002 0.012
Hemoglobin 0.096 0.067
Leukocytes 0.050 0.341
Creatinine −0.014 0.786
Sodium 0.161 0.002 0.018 0.006 0.006
BUN −0.036 0.520
Patient age 0.069 0.186
Body mass index −0.057 0.292
MELD score* −0.137 0.013 - -
ALBI score** −0.225 < 0.001 - -

ALBI, albumin-bilirubin; ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; GGT, gamma-glutamyl transpeptidase; INR, international normalized ratio

*MELD score was not included in the multivariate analysis due to interference with bilirubin

**ALBI score was not included in the multivariate analysis due to interference with albumin and bilirubin