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. 2022 Jan 27;7:7. doi: 10.1038/s41525-021-00278-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Venn diagrams showing the overlap of variants detected between the FJD-pipeline and the commercial pipeline: (a) Illumina -TSCancer, (c) Sophia panel, (e) Illumina-Nextera panel. The bar plots show the average number of variants (variant count) detected by the FJD-pipeline and the commercial pipelines (b) Illumina-TSCancer Panel, (d) Sophia, (f) Illumina- Nextera Panel, in each type of genomic region, the distributions are shown using the mean and standard deviation for visual ease. Significant differences between values are indicated by asterisks: *p < 0.05, **p < 0.01, ***p < 0.001.