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. 2022 Jan 27;5:15. doi: 10.1038/s41746-022-00558-0

Table 4.

Structured-unstructured feature pairs AB with high interaction heterogeneity (IH), where A is a strong risk factor for suicide attempt.

Features Cases Non-cases
Structured (A) Unstructured (B) A B AB expected AB actual A B AB expected AB actual IH
Other, mixed, or unsp. Drug abuse, unsp. Use Suicide attempts 2356 3741 374.53 1003 148 563 3.54 53 77.55
Other, mixed, or unsp. Drug abuse, unsp. Use Section XII 2356 3045 304.85 849 148 403 2.53 43 74.72
Other, mixed, or unsp. Drug abuse, unsp. Use Living on the street 2356 1113 111.43 532 148 154 0.97 36 66.66
Other, mixed, or unsp. Drug abuse, unsp. Use Prison 2356 2043 204.53 825 148 358 2.25 51 62.57
Other, mixed, or unsp. Drug abuse, unsp. Use Intoxications 2356 2663 266.61 889 148 462 2.91 50 60.56
Suicidal ideation Section XII 1820 3045 235.49 1299 127 403 2.17 81 54.69
Other, mixed, or unsp. Drug abuse, unsp. Use Undomiciled 2356 2357 235.97 964 148 408 2.57 55 54.50
Other, mixed, or unsp. Drug abuse, unsp. Use Opioid dependence 2356 1625 162.69 841 148 195 1.23 44 53.86
Suicidal ideation Schizoaffective schizophrenia 1820 676 52.28 223 127 118 0.64 21 52.75
Other, mixed, or unsp. Drug abuse, unsp. Use Sober 2356 3667 367.12 1329 148 723 4.55 76 52.29
Other, mixed, or unsp. Drug abuse, unsp. Use Unspecified bipolar disorder 2356 3488 349.20 932 148 699 4.40 49 48.53
Other, mixed, or unsp. Drug abuse, unsp. Use Schizoaffective schizophrenia 2356 676 67.68 172 148 118 0.74 15 46.44
Opioid abuse, unspec. Use Sober 1305 3667 203.35 710 78 723 2.40 42 46.09
Other, mixed, or unsp. Drug abuse, unsp. Use Methadone 2356 2992 299.54 1165 148 653 4.11 69 45.55
Borderline personality Methadone 582 2992 74.00 139 35 653 0.97 14 43.59
Opioid abuse, unspec. Use Living on the street 1305 1113 61.72 293 78 154 0.51 18 43.28
Opioid type dependence, continuous use Drug seeking 710 463 13.97 96 50 51 0.11 9 37.61
Suicidal ideation Suicidality 1820 2546 196.90 1057 127 380 2.05 58 35.84
Other, mixed, or unsp. Drug abuse, unsp. Use Cluster b 2356 495 49.56 175 148 43 0.27 10 35.70
Unspec. Neurotic disorder Opioid dependence 1003 1625 69.26 191 72 195 0.60 12 35.48

A high IH value indicates that the relationship between A and B changes significantly between case and non-case populations.