Table 1.
Demographics and clinical characteristics
| Participant Characteristic | Cases (N=50) | Controls (N=42) | p-value |
|---|---|---|---|
| Age, years | 73.7 (6.9) | 70.8 (6.4) | 0.04 |
| Female, n (%) | 43 (86%) | 26 (62%) | 0.01 |
| African American, N (%) | 17 (34%) | 18 (43%) | 0.39 |
| BMI, kg/m2 | 36.3 (4.4) | 33.4 (3.1) | 0.001 |
| WOMAC pain score, left knee | 5.2 (5.1) | 2.2 (3.7) | 0.002 |
| WOMAC pain score, right knee | 5.3 (4.9) | 1.8 (3.3) | 0.0001 |
| AUSCAN hand pain score | 5.3 (6.1) | 2.4 (3.9) | 0.01 |
| Percent calories from fat, % | 33.1 (2.6) | 34.2 (4.7) | 0.20 |
| Glucosamine use, n (%) | 2 (0.04%) | 2* (0.05%) | 0.53 |
| NSAID use, n (%) | 33 (66%) | 27* (66%) | 0.99 |
| Maximum KL Grade | |||
| 0 | 0 | 1 (2.4%) | |
| 1 | 0 | 32 (76.2%) | |
| 2 | 2 (4.0%) | 9 (21.4%) | |
| 3 | 13 (26.0%) | 0 | |
| 4 | 21 (42.0%) | 0 | |
| Total knee replacement | 14 (28.0%) | 0 | |
Values are mean (SD) unless otherwise specified; BMI, body mass index; WOMAC, Western Ontario and McMaster Universities Arthritis Index (range 0–20); KL, Kellgren and Lawrence
*
missing data-glucosamine use (n=1)