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. Author manuscript; available in PMC: 2023 Feb 20.
Published in final edited form as: Stat Med. 2021 Nov 16;41(4):769–785. doi: 10.1002/sim.9260

TABLE 2.

Comparison of multilevel approach with the marginal approach and the available case approach from simulation study for continuous outcome where working models were misspecified by omitting an important covariate

β 0 β 1

Emp var ratiob MSE ratiob Emp var ratiob MSE ratiob

Effect strength % Miss. Ra Ya Available case approach Marginal approach Available case approach Marginal approach Available case approach Marginal approach Available case approach Marginal approach

Weak 20 T T 0.994 0.844 0.992 0.845 1.103 0.858 1.104 0.858
T F 0.993 0.847 0.994 0.850 1.104 0.861 1.106 0.862
F T 0.993 0.846 0.991 0.847 1.101 0.861 1.102 0.861
F F 0.993 0.848 1.002 0.851 1.102 0.863 1.105 0.864

35 T T 1.002 0.671 0.971 0.672 1.042 0.667 1.040 0.667
T F 1.009 0.679 0.983 0.684 1.054 0.676 1.053 0.677
F T 0.997 0.671 0.966 0.671 1.037 0.668 1.036 0.669
F F 1.003 0.679 0.991 0.684 1.050 0.676 1.049 0.677

Strong 20 T T 0.901 0.891 0.626 0.891 0.965 0.907 0.905 0.907
T F 0.964 0.935 0.707 0.985 1.023 0.954 0.968 0.963
F T 0.892 0.913 0.620 0.912 0.951 0.928 0.892 0.928
F F 0.996 0.937 1.385 0.973 1.021 0.953 1.136 0.965

35 T T 0.877 0.739 0.398 0.738 0.915 0.762 0.824 0.762
T F 1.123 0.857 0.602 1.010 1.151 0.866 1.061 0.886
F T 0.811 0.795 0.368 0.795 0.848 0.819 0.764 0.819
F F 1.044 0.890 2.016 1.007 1.058 0.896 1.338 0.946
a

T = Working model specified correctly. F = Working model misspecified by excluding the covariate Z3,ij.

b

Ratio comparing multilevel approach to corresponding comparison method.