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. 2022 Jan 14;8:799516. doi: 10.3389/fmed.2021.799516

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Copyright © 2022 Zhang, Zhao, Su, Wang, Chen, Shen, Ma, Zhu, Chen, Jiang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplots showing the plasma level of six candidate biomarkers in the discovery cohort using Quantibody Custom Array. (A) Growth differentiation factor 15 (GDF15), (B) uPAR, (C) IL1RL1, (D) NGAL, (E) IL6, and (F) FABP3 plasma levels of AKI group (n = 17) and control group (n = 21) at 4 time point, pre (pre-operation), day0 (ICU arrival after surgery), day1 and day2, were measured and compared. Boxplot represents the median and interquartile range (IQR), whiskers adjacent values (extreme values within 1.5 IQR of nearest quartile), and points outside values. ***p < 0.001, **p < 0.01, *p < 0.05, ns. p > 0.05.