Skip to main content
. 2022 Jan 14;12:805883. doi: 10.3389/fimmu.2021.805883

Table 2.

Univariate and multivariable Cox regression analysis of the EMT-related genes and overall survival in different patient sets.

Variable Univariable model Multivariable model
HR 95% CI p-Value HR 95% CI p-Value
Training set (n = 153)
Age 2.024 1.115–3.675 0.021 1.698 0.901–3.199 0.101
histological_type 2.888 1.754–4.755 3.05E−05 1.625 0.929–2.841 0.089
Grade 2.939 1.176–7.342 0.021 1.248 0.461–3.381 0.663
Stage 4.446 2.680–7.374 7.53E−09 3.361 1.914–5.902 2.43E−05
riskScore 1.105 1.075–1.136 1.53E−12 1.084 1.054–1.116 3.34E−08
Testing set (n = 358)
Age 1.397 0.633–3.086 0.408
histological_type 3.501 1.609–7.618 0.002 2.903 1.264–6.670 0.012
Grade 5.407 0.732–39.947 0.098
Stage 3.413 1.575–7.398 0.002 2.251 0.974–5.202 0.058
riskScore 1.036 1.012–1.061 0.003 1.033 1.006–1.061 0.016
Entire set (n = 511)
Age 1.778 1.112–2.843 0.016 1.498 0.915–2.454 0.108
histological_type 3.044 2.003–4.624 1.84E−07 1.940 1.219–3.087 0.005
Grade 3.363 1.467–7.710 0.004 1.479 0.609–3.592 0.387
Stage 4.116 2.700–6.275 4.82E−11 3.014 1.892–4.799 3.38E−06
riskScore 1.048 1.033–1.062 6.81E−11 1.038 1.021–1.054 5.15E−06

EMT, epithelial–mesenchymal transition.