Table 2.
The association of different types of TILs with tumor prognosis.
| The types of TILs | Reference | Prognosis | Tumor types |
|---|---|---|---|
| CD8+ cell | (30, 37–40) | Good | Colorectal cancer etc. |
| Th1 cell | (21, 25, 41, 52) | Good | Colorectal cancer etc. |
| Th2 cell | (53, 54) | Good | Hodgkin lymphoma; Breast cancer |
| (55–57) | Poor | Ovarian cancer; Pancreatic cancer; Gastric cancer | |
| Th17 cell | (58–61) | Good | Esophageal squamous cell carcinoma; Gastric adenocarcinoma; Ovarian cancer; Squamous cervical cancer |
| (62, 63) | Poor | Non-small cell lung cancer; Hepatocellular carcinoma | |
| Treg cell | (64–66) | Good | Nasopharyngeal carcinoma; Head and neck cancer; Urinary bladder cancer |
| (67–69) | None | Anal squamous cell carcinoma; Glioma; Glioblastomas | |
| (70) | Poor | Ovarian carcinoma | |
| NK cell | (71–76) | Good | Metastatic prostate cancer; Non-small cell lung cancer; Colorectal cancer; Mantle cell lymphoma |
| (77, 78) | Poor | Infiltrating ductal carcinoma of breast; Digestive cancer | |
| B cell | (79–83) | Good | Hepatocellular carcinoma with lymphocytic infiltration; Melanoma; Ovarian cancer; Non-small cell lung cancer; Stage IB cervical squamous cell carcinoma |
| (84, 85) | Poor | Ovarian cancer; Breast cancer |