TABLE 1.

Application of pseudotyped Vesicular Stomatitis Virus (VSV).

Virus	Viral protein	Research area and application	Reporter	References
Crimean-Congo hemorrhagic fever Virus	GP	Vaccine, viral entry mechanism, and neutralizing assay	Luciferase	Suda et al., 2016; Rodriguez et al., 2019
Ebola virus	GP	Vaccine and drug testing	GFP	Takada et al., 1997; Geisbert and Feldmann, 2011; Lennemann et al., 2017; Saito et al., 2020
Marburg virus	GP	Vaccine and drug testing	GFP	Geisbert and Feldmann, 2011; Zhang et al., 2017; Saito et al., 2020
Lassa virus	GP	Entry and receptor mechanism, and neutralization assays	GFP	Kunz et al., 2005; Hastie et al., 2017
Nipah virus	G/F	Fusion mechanism and neutralization assays	GFP and SEAP	Kaku et al., 2009, 2012; Tamin et al., 2009; Contreras et al., 2021
Rift Valley virus	GP	Serological assays	Luciferase	Bukbuk et al., 2014
MERS	Spike	Vaccine, neutralization assays, and receptor evaluation	Luciferase and GFP	Fukuma et al., 2015; Liu et al., 2018; Lester et al., 2019
SARS-CoV	Spike	Vaccine, entry mechanism, and neutralization assays	GFP	Fukushi et al., 2006, 2008; Ge et al., 2006; Kapadia et al., 2008
SARS-CoV-2	Spike	Neutralization assays, entry mechanism, treatment testing, vaccine, and vaccine efficacy	GFP, luciferase, and SEAP	Condor Capcha et al., 2020; Gasbarri et al., 2020; Collier et al., 2021; Malherbe et al., 2021; Tolah et al., 2021; Verma et al., 2021

GP, glycoprotein; GFP, green fluorescent protein; SEAP, secreted alkaline phosphatase; F, fusion; G, attachment.