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. 2022 Jan 14;12:785247. doi: 10.3389/fimmu.2021.785247

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Copyright © 2022 Endmayr, Tunc, Ergin, De Rosa, Weng, Wagner, Yu, Fichtenbaum, Perkmann, Haslacher, Kozakowski, Schwaiger, Ricken, Hametner, Klotz, Dutra, Lechner, de Simoni, Poppert, Müller, Pirker, Pirker, Angelovski, Valach, Maestri, Guida, Ricciardi, Frommlet, Sieghart, Pinter, Kircher, Artacker, Höftberger and Koneczny

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Correlation between serum IgG4 and total IgG concentrations (statistical analysis with Spearman correlation in datasets with at least 3 datapoints). (A) healthy controls, (B) neurometabolic controls, (C) IgG4-RLD, (D) LGI1, (E) Caspr2, (F) NF155, (G) CNTN1, Caspr1 and (H) MuSK. In (F), the triangular data point indicates a patient that was excluded from the statistical analysis due to the presence of pan-NF antibodies instead of NF155 antibodies and severe concomitant autoimmune diseases. Caspr1, contactin-associated protein-like 1; Caspr2, contactin-associated protein-like 2; CNTN1, contactin 1; IgG, immunoglobulin type G; IgG4, immunoglobulin type G subclass 4; IgG4-RLD, IgG4-related disease; LGI1, leucine-rich glioma inactivated protein- 1; MuSK, muscle-specific kinase; NF155, neurofascin 155.