Table 1.
Enriched GO-terms of intersection genes
| ID | Description | Gene | Count | p | q |
|---|---|---|---|---|---|
| GO:0071222 | cellular response to lipopolysaccharide | TLR4/NLRP3/IL6/IL1B/CX3CR1/CCR5 | 6 | 4.48E-07 | 1.32E-07 |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | TLR4/NLRP3/IL6/IL1B/CX3CR1/AGT | 6 | 7.63E-07 | 2.26E-07 |
| GO:0071219 | cellular response to molecule of bacterial origin | TLR4/NLRP3/IL6/IL1B/CX3CR1/CCR5 | 6 | 4.48E-07 | 1.32E-07 |
| GO:0032496 | response to lipopolysaccharide | TLR4/NLRP3/IL6/IL1B/CX3CR1/CCR5 | 6 | 1.84E-06 | 5.44E-07 |
| GO:0071216 | cellular response to biotic stimulus | TLR4/NLRP3/IL6/IL1B/CX3CR1/CCR5 | 6 | 5.74E-07 | 1.70E-07 |
| GO:0009897 | external side of plasma membrane | TLR4/CX3CR1/CCR5/ACE/F2 | 5 | 2.26E-05 | 9.52E-06 |
| GO:0048018 | receptor ligand activity | IL6/IL1RN/IL1B/AGT/F2 | 5 | 0.000196 | 6.96E-05 |
| GO:0030546 | signaling receptor activator activity | IL6/IL1RN/IL1B/AGT/F2 | 5 | 0.000196 | 6.96E-05 |
| GO:0008083 | growth factor activity | IL6/AGT/F2 | 3 | 0.000753 | 0.000268 |
| GO:0019955 | cytokine binding | IL1RN/CX3CR1/CCR5 | 3 | 0.000753 | 0.000268 |
| GO:0070851 | growth factor receptor binding | IL6/IL1RN/IL1B | 3 | 0.000753 | 0.000268 |
Notes: Count value represents the number of target genes that core genes belong to in the term, and p was corrected by Benjamini-Hochberg method. And q value was estimated for false discovery rate control. The values p < 0.01 and q < 0.01 were considered statistically significant.