Figure 1.

Experimental scheme and effects of skeletal muscle satellite cell-derived mesenchymal stem cells (SkMSCs) on body weight, spleen weight, and liver weight in binge ethanol-exposed mice. Eight-week-old C57BL/6 female mice were treated with binge ethanol and sacrificed on day 1. (A) Experimental design of the binge ethanol-induced liver injury model. (B-D) Body, spleen, and liver weight were measured after the third injection of ethanol. n = 5-17 mice per group. Scatter plot: horizontal bar, median. S, sham; E, binge ethanol; M, SkMSCs. Significance between treated groups was determined using Mann-Whitney U test. * P < 0.05, *** P < 0.001; ns, no statistical significance.