Figure 4.

Effect of skeletal muscle satellite cell-derived mesenchymal stem cells (SkMSCs) on intestinal histopathology. Eight-week-old C57BL/6 female mice were treated with binge ethanol. Mice were sacrificed on day 1, and intestinal tissues (ileum) were fixed and stained with H&E. Representative images are shown. Histologic scores were evaluated using H&E slides. (A) H&E staining of small intestine (ileum); (B) inflammation scores; (C) villus lengths; (D) crypt lengths (n = 5-13 mice per group). Scatter plot: horizontal bar, median. S, sham; E, ethanol binge; M, SkMSCs. Significance between treated groups was determined using Mann-Whitney U test. * P < 0.05, *** P < 0.001; ns, no statistical significance.