Table 2.
Risk Factors of Malignant Neoplasms in Hospitalized Patients with Liver Transplant Status in the United States- from 2016 to 2018.
| Malignant Neoplasms | Odds Ratio (95%CI) | P value | Adjusted Odds Ratio (95%CI) |
P value |
|---|---|---|---|---|
| Univariate logistic regression1 | Multivariate logistic regression2 | |||
| Sex, Female vs Male | 0.660 (0.597 - 0.730) | <.001 | 0.712 (0.643 - 0.788) | <.001 |
| Age groups (y) | ||||
| <=17 | Reference | NA | Reference | NA |
| 18-49 | 0.989 (0.746 - 1.312) | NS | 0.976 (0.734 - 1.299) | NS |
| 50-59 | 1.830 (1.413 - 2.370) | <.001 | 1.683 (1.294 - 2.190) | <.001 |
| 60-69 | 2.317 (1.812 - 2.964) | <.001 | 2.091 (1.625 - 2.690) | <.001 |
| >=70 | 2.918 (2.265 - 3.758) | <.001 | 2.685 (2.067 - 3.488) | <.001 |
| Race/ethnicity | <.001 | |||
| White | Reference | NA | Reference | NA |
| Black | 0.663 (0.550 - 0.798) | <.001 | 0.802 (0.663 - 0.970) | <.05 |
| Hispanic | 0.668 (0.572 - 0.781) | <.001 | 0.759 (0.647- 0.889) | <.001 |
| Asian or pacific islander | 1.204 (0.931 - 1.557) | NS | 1.219 (0.938 - 1.585) | NS |
| Native American | 0.937 (0.789 - 1.113) | NS | 0.789 (0.401 - 1.552) | NS |
| Median socioeconomic status by national quartiles | ||||
| 0-25 | Reference | NA | Reference | NA |
| 25-50 | 1.180 (1.028 - 1.353) | NS | 1.117 (0.971 - 1.285) | NS |
| 50-75 | 1.371 (1.201 - 1.566) | <.001 | 1.285 (1.121 - 1.473) | <.001 |
| 75-100 | 1.289 (1.121 - 1.482) | NS | 1.161 (1.004 - 1.342) | <.05 |
| Admission Type, Elective vs Non-elective | 1.731 (1.544 - 1.942) | <.001 | 1.731 (1.540 - 1.946) | <.001 |
| Hospital Bed Size | ||||
| Small | Reference | NA | Reference | NA |
| Medium | 1.185 (0.990 - 1.417) | NS | 1.277 (1.065 - 1.532) | <.005 |
| Large | 1.329 (1.134 - 1.558) | <.001 | 1.473 (1.253 - 1.732) | <.001 |
| Location/teaching status of hospital | ||||
| Rural | Reference | NA | Reference | NA |
| Urban nonteaching | 0.909 (0.694 - 1.191) | NS | 0.883 (0.669 - 1.164) | NS |
| Urban teaching | 1.092 (0.861- 1.387) | NS | 1.162 (0.908 - 1.487) | NS |
| Hospital region | ||||
| Northeast | Reference | NA | Reference | NA |
| Midwest or North Central | 0.863 (0.751 - 0.993) | NS | NA | NS |
| South | 0.793 (0.698 - 0.901) | <.001 | NA | NS |
| West | 0.827 (0.715 - 0.956) | NS | NA | NS |
| Discharge Characteristics | ||||
| Routine Discharge | Reference | NA | Reference | NA |
| Transfer to Short-term Hospital | 1.019 (0.801 - 1.297) | NS | 1.093 (0.856 - 1.397) | NS |
| Transfer to other facilities | 1.104 (0.953 - 1.278) | NS | 0.951 (0.818 - 1.106) | NS |
| Home Health Care (HHC) | 1.547 (1.375 - 1.740) | <.001 | 1.342 (1.190 - 1.514) | <.001 |
| Smoking | 1.273 (1.156 - 1.402) | <.001 | 1.121 (1.013 - 1.240) | <.05 |
| Alcoholic cirrhosis | 1.360 (1.053 - 1.757) | 0.0186 | 1.298 (1.0 - 1.687) | 0.0507 |
| Hepatitis B | 1.860 (1.410 - 2.454) | <.001 | 1.554 (1.166 - 2.071) | <.01 |
| Hepatitis C | 1.365 (1.186 - 1.570) | <.001 | 1.237 (1.069 - 1.431) | <.01 |
| HIV | 1.276 (0.704 - 2.314) | NS | NA | NS |
| Immunosuppression | 1.115 (0.667 - 1.863) | NS | NA | NS |
| Opioid | 1.276 (0.995 - 1.636) | 0.0546 | 1.362 (1.056 - 1.756) | <.05 |
| PSC | 1.367 (0.589 - 3.177) | NS | NA | NS |
1Univariate logistic regression is performed in SAS software with PROC Logistic.
2Mutivariate logistic regression is performed with stepwise logistic regression with a 0.15 significance level of entry and 0.10 significance level of stay. NS: Not statistically significant.