TABLE 3.
Significant pathways and gene ontology terms found in g:profiler for the differentially expressed genes between LF embryos and HF embryos.
| Pathway or gene ontology term | Pathway ID | Adj. p-value | Genes represented |
|---|---|---|---|
| Highly expressed in LF embryos | |||
| sterol biosynthetic process | GO:0016126 | 1.51E-08 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| cholesterol biosynthetic process | GO:0006695 | 1.42E-06 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, SC5D |
| secondary alcohol biosynthetic process | GO:1902653 | 1.42E-06 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, SC5D |
| steroid biosynthetic process | GO:0006694 | 8.33E-06 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| sterol metabolic process | GO:0016125 | 9.39E-06 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| lipid biosynthetic process | GO:0008610 | 3.63E-05 | HMGCS1, PMVK, MSMO1, SCD, IDI1, FDFT1, HMGCR, PTGS2, FDPS, SC5D, ACSL3 |
| isoprenoid biosynthetic process | GO:0008299 | 5.45E-05 | HMGCS1, PMVK, IDI1, HMGCR, FDPS |
| isoprenoid metabolic process | GO:0006720 | 6.19E-05 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, FDPS |
| organic hydroxy compound biosynthetic process | GO:1901617 | 2,59E-04 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| cholesterol metabolic process | GO:0008203 | 4,00E-04 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, SC5D |
| secondary alcohol metabolic process | GO:1902652 | 5,45E-04 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, SC5D |
| alcohol biosynthetic process | GO:0046165 | 8,84E-04 | HMGCS1, PMVK, IDI1, FDFT1, HMGCR, SC5D |
| steroid metabolic process | GO:0008202 | 9,62E-04 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| lipid metabolic process | GO:0006629 | 5,31E-03 | HMGCS1, PMVK, MSMO1, SCD, IDI1, FDFT1, HMGCR, PTGS2, FDPS, GPLD1, SC5D, ACSL3 |
| small molecule metabolic process | GO:0044281 | 2,17E-02 | HMGCS1, PMVK, AK1, SCD, IDI1, FDFT1, HMGCR, MTHFD2, PTGS2, Non-annotated gene: ENSBTAG00000014127, GNG2, SC5D, PNP, ACSL3 |
| cellular lipid metabolic process | GO:0044255 | 4,60E-02 | HMGCS1, PMVK, SCD, IDI1, FDFT1, HMGCR, PTGS2, FDPS, GPLD1, ACSL3 |
| small molecule biosynthetic process | GO:0044283 | 4,94E-02 | HMGCS1, PMVK, SCD, IDI1, FDFT1, HMGCR, PTGS2, SC5D |
| Metabolic pathways | KEGG:01100 | 2,91E-08 | HMGCS1, Non-annotated gene: ENSBTAG00000054516, PMVK, MSM O 1, AK1, SCD, IDI1, FDFT1, HMGCR, MTHFD2, PTGS2, Non-annotated gene: ENSBTAG00000014127, GNG2, FDPS, GPLD1, SC5D, PNP, ACSL3 |
| Terpenoid backbone biosynthesis | KEGG:00900 | 8,78E-08 | HMGCS1, PMVK, IDI1, HMGCR, FDPS |
| Steroid biosynthesis | KEGG:00100 | 4,59E-04 | MSMO1, FDFT1, SC5D |
| PPAR signaling pathway | KEGG:03320 | 1,10E-02 | HMGCS1, SCD, ACSL3 |
| Cholesterol biosynthesis | REAC:R-BTA-191273 | 3,13E-08 | MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| Metabolism of steroids | REAC:R-BTA-8957322 | 2,02E-05 | MSMO1, IDI1, FDFT1, HMGCR, SC5D |
| Metabolism of lipids | REAC:R-BTA-556833 | 8,38E-04 | MSMO1, IDI1, FDFT1, HMGCR, PTGS2, SC5D, ACSL3 |
| Metabolism | REAC:R-BTA-1430728 | 1,72E-02 | MSM O 1, IDI1, FDFT1, HMGCR, MTHFD2, PTGS2, SC5D, PNP, ACSL3 |
| Cholesterol Biosynthesis | WP:WP1070 | 2,61E-16 | HMGCS1, PMVK, MSMO1, IDI1, FDFT1, HMGCR, FDPS, SC5D |
| SREBP signalling | WP:WP3194 | 1,25E-05 | HMGCS1, IDI1, FDFT1, HMGCR, FDPS |
| SREBF and miR33 in cholesterol and lipid homeostasis | WP:WP3137 | 2,14E-02 | HMGCS1, HMGCR |
| Statin Pathway | WP:WP1041 | 4,16E-02 | FDFT1, HMGCR |
| Highly expressed in HF embryos | |||
| G protein complex (CACNA1A, GNB1, GNG2) | CORUM:3216 | 4,99E-02 | GNG2 |