TABLE 2.
X-ray structures containing chloride anions at the C-terminus of the M2 proton channel.
| PDB ID | Resolution (Å) | Construct (mutant) | Experimental conditions | References |
|---|---|---|---|---|
| 5C02 | 1.59 | 22–46 (S31N) | pH: 8.0 T: 283/100 K a | Thomaston and DeGrado, (2016) |
| LCP (OG) b | ||||
| 6BMZ | 2.63 | 22–46 | pH: 7.0 T: 293/100 K | Thomaston et al. (2018) |
| LCP (MNG-3-C8) b | ||||
| 6NV1 | 2.50 | 22–46 (V27A) | pH: 7.5 T: 293/100 K | Thomaston et al. (2020) |
| LCP (MNG-3-C8) | ||||
| 6US8 | 1.70 | 22–46 | pH: 7.5 T: 293/100 K | Thomaston et al. (2021) |
| LCP (MNG-3-C8) | ||||
| 6US9 | 2.00 | 22–46 | pH: 8.5 T: 293/100 K | Thomaston et al. (2021) |
| LCP (MNG-3-C8) |
aTemperature of crystallization/temperature of data collection (values in Kelvin).
bObtained consideringa lipidic cubic phase (LPC) formed by monoolein and octyl glucopyranoside (OG) or maltose neopentyl glycol analogue (MNG-3-C8).