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. 2022 Jan 14;15:778769. doi: 10.3389/fnana.2021.778769

TABLE 5.

Summary of atlas evaluation on PET.

Atlas-judge [ 11 C]metergoline (n = 64) [ 18 F]FAHA (n = 24) [ 11 C]rolipram (n = 48)
Intraclass correlation coefficient 0.81 0.96 0.96
Dice similarity coefficient 0.64 ± 0.05 0.58 ± 0.04 0.62 ± 0.08
Bland-Altman Atlas Bias (%) −8.17 −7.86 −5.29
Kolmogorov-Smirnov test of normality p 0.06 0.94 0.36

Inter-judge [ 11 C]metergoline (n = 64) [ 18 F]FAHA (n = 24) [ 11 C]rolipram (n = 48)

Intraclass correlation coefficient 0.97 0.99 0.98
Bland-Altman Judge A Bias (%) −2.23 −3.77 −3.22
Kolmogorov-Smirnov Test of Normality p 0.07 0.80 0.01

Intra-judge (judge A/judge R) [11C]metergoline (n = 4/n = 4) [18F]FAHA (n = 8/n = 6) [11C]rolipram (n = 4/n = 4)

Intraclass correlation coefficient (Judge A/Judge R) 0.87/0.98 0.99/0.99 0.98/0.91
CV (%) (judge A/judge R) 1.24/0.68 1.06/0.57 1.00/1.90