Table 1.
Event | Screening | Visit 1 Vit D or Placebo (Baseline) |
Visit 2 Compliance testing/Refill (4 wks from Baseline) |
Visit 3 Compliance testing/Refill (8 wks from Baseline) |
Visit 4 Compliance testing/Refill (12 wks from Baseline) |
Visit 5 (8 wks from SRP) (16 wks from Baseline) |
---|---|---|---|---|---|---|
Medical history | ☓ | |||||
Informed consent | ☓ | ☓ | ||||
Intensive SRP | ☓ | |||||
25(OH)D | ☓ | ☓ | ☓ | |||
Peripheral blood, Whole saliva | ☓ | ☓ | ☓ | ☓ | ||
Gingival biopsy | ☓ | ☓ | ☓ | |||
Vit D supplementation | ☓ | ☓ | ☓ | ☓ | ||
Sub-gingival plaque sample | ☓ | ☓ | ☓ | |||
Check gingival healing | ☓ | ☓ |