Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 24;10(1):e003024. doi: 10.1136/jitc-2021-003024

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Cancer immunity cycle and therapy targets.1 17 Adapted from Chen and Mellman,17 with permission from Elsevier. A2AR, adenosine A2A receptor; CAR-T, chimeric antigen receptor T cell therapy; CD, cluster of differentiation; CTLA-4, cytotoxic T-lymphocyte antigen 4; DC, dendritic cell; ICI, immune checkpoint inhibitor; IFN-α, interferon alpha; IL, interleukin; LAG-3, lymphocyte-activation gene three protein; PD-1, programmed death-1; PD-L1, programmed death ligand 1; STING, stimulator of interferon genes; TIM-3, T-cell immunoglobulin domain and mucin domain-3; TLR, toll-like receptor; TME, tumor microenvironment.