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. 2022 Jan 14;12:780392. doi: 10.3389/fendo.2021.780392

Table 4.

Results of IVF pregnancy outcomes between treatment protocol groups obtained using generalized equation model analyses with adjusted repeated embryo transfer cycles for a given patient.

Comparison Ongoing pregnancy Live birth
OR (95% CI) p-value OR (95% CI) p-value
Group comparison
 Study group versus control group (ref.) (180 FET cycles) 1.13 (0.55, 2.32) 0.7455 1.50 (0.65, 3.49) 0.3429
 Protocol A versus protocol B (ref.) (180 FET cycles) 0.77 (0.37, 1.58) 0.4719 0.66 (0.29, 1.54) 0.3365
Subgroup comparison (ref.: study group with protocol B)
 Control group with protocol A vs. ref. (150 FET cycles) 0.71 (0.29, 1.76) 0.4590 0.5 (0.17, 1.43) 0.1949
 Control group with protocol B vs. ref. (102 FET cycles) 0.74 (0.25, 2.20) 0.5892 0.47 (0.14, 1.58) 0.2221
 Study group with protocol A vs. ref. (106 FET cycles) 0.61 (0.20, 1.83) 0.3770 0.47 (0.13, 1.66) 0.2390

OR, odds ratio; CI, confidence interval; FET, frozen embryo transfer; study group, patients received cotreatment of clomiphene citrate and letrozole in mild ovarian stimulation; control group, patients received conventional ovarian stimulation; protocol A, patients received ovarian stimulation with gonadotropin-releasing hormone GnRH antagonist protocol; protocol B, patients received ovarian stimulation with progestin-primed ovarian stimulation (PPOS) protocol.