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. 2022 Jan 27;22:94. doi: 10.1186/s12879-022-07076-0

Table 3.

Incidence rates according to exposure to DAA treatment for HCC, all-cause mortality, and liver transplant in all 55 patients with a Meld score > 20 or Child–Pugh score C

Not exposed to DAA
N = 12
Exposed to DAA
N = 43
P-value
n/pyr Incidence/100pyrs
(95% CI)
n/pyr Incidence/100pyrs
(95% CI)
HCC (N = 11) 7/22 31.2 (12.5–64.3) 4/100 4.0 (1.1–10.3) 0.001
All-cause mortality (N = 20) 10/26 38.5 (18.5–70.8) 10/112 9.0 (4.3–16.5) 0.002
Liver related mortality (N = 13) 6/26 23.1 (8.5–50.2) 7/112 6.3 (2.5–12.9) 0.026
Non-liver related mortality (N = 5) 2/26 7.7 (0.9–27.8) 3/112 2.7 (0.6–7.9) 0.275
Liver transplant (N = 9) 4/20 20.0(5.5–51.3) 5/92 5.4 (1.8–12.7) 0.07