Table 1.
Characteristics of the female OI cohort with pregnancies
| OI female cohort | Total OI cohort 50 patients |
|---|---|
| Type I, N (%) | 28/36 (77.8) |
| Genetically confirmed (%) | 30/50 (60.0) |
| Number of fractures before pregnancy < 5, N (%) | 15/49 (30.6) |
| Number of fractures before pregnancy 5–10, N (%) | 9/49 (18.4) |
| Number of fractures before pregnancy 11–50, N (%) | 22/49 (44.9) |
| Number of fractures before pregnancy > 50, N (%) | 4/49 (8.2) |
| Age at OI diagnosis (years, mean ± SD) | 13.7 ± 14.8 |
| Blue sclera, N (%) | 32/38 (84.2) |
| Deafness, N (%) | 12/40 (30.0) |
| Joint Hyperlaxity, N (%) | 20/38 (52.6) |
| Scoliosis or kyphosis, N (%) | 20/39 (51.3) |
| Spine surgery or telescopic rods, N (%) | 10/48 (21.3) |
| Wheelchair or walking stick, N (%) | 8/46 (18.6) |
| Time between last fracture and pregnancy (years, mean ± SD) | 10.2 ± 7.7 |
| Bisphosphonates before pregnancy, N (%) | 10/50 (20.0) |
| Time since bisphosphonates (years, mean ± SD) | 8.1 ± 4.9 |
| Height (cm, mean ± SD) | 153.8 ± 12.7 |
| Weight (kg, mean ± SD) | 56.8 ± 12.8 |
| BMI (kg/m2, mean ± SD) | 24.1 ± 4.9 |
Bold refers to %