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. 2022 Jan 7;23(3):204. doi: 10.3892/etm.2022.11127

Figure 3.

Figure 3

Effects of MAGEA6 on the invasion ability of Eca109 cells. (A) Invasion assay images of Eca109-MAGEA6-siRNA, Eca109-MAGEA6-3.1 and Eca109-3.1 cells, which were captured under x10 magnification after 42 h. (B) Reverse transcription-quantitative PCR verification of MAGEA6 overexpression in Eca109 cells (*P<0.05 vs. Eca109-3.1). (C) Compared with the si-NC, siRNA3 was found to be the most effective at knocking down MAGEA6 expression out of the three designed siRNAs (*P<0.01 vs. Eca109-3.1 and si-NC). (D) Quantification of cell invasiveness in Eca109-MAGEA6-siRNA cells compared with Eca109-3.1 and Eca109-MAGEA6-3.1 cells (*P<0.05 and **P<0.01 vs. Eca109-3.1). MAGEA6, melanoma antigen gene family A; si, short interfering; NC, negative control.