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. 2022 Jan 28;23:85. doi: 10.1186/s12864-021-08269-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — rs5011804-by-diagnosis interaction analysis visualizations. The diagnosis × allelic dosage of the novel SNP rs5011804 was plotted against the average level of biomarker for each of several diagnostic and imaging biomarkers. Adjacent to each graph shown in red is the relevant p-value of the interaction effect found. Additionally, a similar figure showing the median and interquartile range has been made and is available in the Supplementary Material (Figure S4)