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. Author manuscript; available in PMC: 2022 Jan 28.
Published in final edited form as: Nat Methods. 2021 Aug 26;18(9):1013–1026. doi: 10.1038/s41592-021-01206-3

Fig. 1 |. Timeline of EV imaging milestones and broad overview of microscopy techniques to resolve EVs at different scales.

Fig. 1 |

a, Timeline of imaging milestones in EV research. EM, electron microscopy. Refs. 2,10,17,19,22,34,38,47,63,68,128,129,131–136. b, Schematic of the resolution range of different microscopic approaches to resolve EVs at increasing resolution.