Table 6.

Comparison of the least squares means (±SE) of the relative concentration (arbitrary units) of blood metabolites for animals that survived and died from BRD¹

Metabolite	Survived (n = 121)	Died (n = 16)	P-value
1-Methyl-histidine	1.11 ± 0.017	1.17 ± 0.046	0.195
3-Hydroxyisobutyrate	12.49 ± 0.243	13.73 ± 0.665	0.081
α Glucose chain	1.22 ± 0.030	1.47 ± 0.083	0.004
Acetate	7.58 ± 0.258	5.73 ± 0.700	0.015
Acetone	2.96 ± 0.063	3.12 ± 0.183	0.416
Alanine	6.71 ± 0.075	7.01 ± 0.213	0.184
Choline	5.88 ± 0.090	5.81 ± 0.249	0.773
Citrate	1.65 ± 0.021	1.51 ± 0.058	0.029
Creatine	11.47 ± 0.244	12.74 ± 0.670	0.077
Creatinine	11.47 ± 0.230	11.79 ± 0.647	0.634
Dimethyl sulfone	2.55 ± 0.033	2.44 ± 0.091	0.242
Ethanol	28.60 ± 0.244	28.08 ± 0.665	0.465
Formate	0.45 ± 0.012	0.43 ± 0.032	0.467
Glucose	17.65 ± 0.299	18.20 ± 0.623	0.409
Glutamate	3.61 ± 0.046	3.58 ± 0.125	0.811
Glutamine	2.18 ± 0.035	2.15 ± 0.097	0.796
Glycine	12.98 ± 0.198	11.60 ± 0.541	0.018
Glycoprotein acetyls	13.05 ± 0.222	13.12 ± 0.605	0.912
Hydroxybutyrate	6.98 ± 0.068	7.58 ± 0.193	0.004
Hydroxyisobutyrate	2.09 ± 0.027	2.04 ± 0.074	0.505
Isobutyrate	2.69 ± 0.025	2.67 ± 0.069	0.774
Isoleucine	14.51 ± 0.196	15.42 ± 0.537	0.114
Isopropanol	13.90 ± 0.137	13.56 ± 0.376	0.406
Lactate	17.08 ± 0.402	16.89 ± 1.141	0.888
Leucine	7.22 ± 0.092	8.04 ± 0.253	0.003
Low Density Lipid	17.07 ± 0.345	15.40 ± 0.940	0.099
Mannose	1.00 ± 0.022	1.09 ± 0.061	0.185
Methanol	10.10 ± 0.099	9.57 ± 0.275	0.068
Phenylalanine	0.47 ± 0.010	0.54 ± 0.028	0.015
Pyruvate	6.31 ± 0.129	7.28 ± 0.349	0.010
Succinate	1.80 ± 0.031	1.75 ± 0.091	0.579
Tyrosine	0.47 ± 0.010	0.47 ± 0.027	0.912
Unsaturated lipid	3.47 ± 0.091	3.33 ± 0.251	0.616
Valine	5.39 ± 0.087	5.58 ± 0.237	0.458

¹Metabolites in bold were significantly different in concentration between animals that survived and those that died.