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. 2022 Jan 14;12:794780. doi: 10.3389/fimmu.2021.794780

Table 1.

Lipinski filter and ADMET properties of psilacetin, psilocin, and psilocybine.

Drugs Lipinski Rule of Five Carcinogen Drug likeness Violations
Mass H-donor H-acceptor LogP Molar Refractivity
Psilacetin 246 1 3 2.2 71.9 No Qualified 0
Psilocin 204 2 2 2.0 62.2 No Qualified 0
Psilocybine 284 3 5 1.7 73.2 No Qualified 0