Table 4.

Research questions and considerations for future studies.

Unanswered future research questions	Considerations
What type(s) of exercise is(are) effective to address anthracycline-induced cardiotoxicity?	Modality of exercise (aerobic, resistance, or combined); cancer type; treatments.
What is the ideal time during the cancer continuum to intervene?	Pre-treatment, during treatment, or following treatment.
What is the optimal duration of an exercise intervention?	Timing of intervention, duration of exercise sessions, length of intervention, age of participant, diagnosis, presence of comorbid conditions.
Large, multi-center studies to better understand the feasibility and effectiveness of exercise to address anthracycline-induced cardiotoxicities.	Timing of intervention in treatment timeline, resources, setting of intervention (in-clinic/supervised, home-based/unsupervised, virtual/supervised, hybrid), availability of resources.