Table 2.

Renal Function and Acid Base Balance at Commencement of CRRT

Blood results	Case 1		Case 2		Case 3		Case 4
	CRRT 1	CRRT 2	CRRT 1	CRRT 2	CRRT 1	CRRT 2	CRRT 1	CRRT 2
Time, h	0	+4	0	+12	0	+3	0	+9
Urea, mmol/L	4.5		8.9	4.6	22.8		31.9	25.3
Creatinine, μmol/L	163		224	160	489		1230	931
pH	7.00	6.99	7.14	6.99	6.74	7.02	6.78	6.91
Fio2	0.4	0.4	0.4	0.4	0.4	0.3	0.7	0.3
Pao2, mm Hg	249	240	142	89	246	124	258	96
Paco2, mm Hg	33	34	45	45	21	18	24	24
Bicarbonate, mmol/L	8	8	15	11	3	4	4	5
Base excess, mmol/L	–22.3	–22.8	–13.7	–20.3	–31.0	–24.7	–30.0	–26.6
Anion gap, mmol/L	43	41	29	34	44	38	38	35
Lactate, mmol/L	25.4	29.2	22.2	25.0	28.1	24.8	17.0	17.0

Abbreviations: Fio₂, fraction of inspired oxygen; Paco₂, partial pressure carbon dioxide in arterial blood; Pao₂, partial pressure oxygen in arterial blood.

Normal range: anion gap, 4 to 13 mmol/L; base excess, −2 to +2 mmol/L; bicarbonate, 22 to 28 mmol/L; creatinine, 36 to 73 μmol/L; lactate, 0.5 to 2.2 mmol/L; Paco₂, 35 to 45 mm Hg; Pao₂, 83 to 108 mm Hg; pH, 7.35 to 7.45; and urea, 2.9 to 8.2 mmol/L.