Fig 9. Cutoff frequencies of dynamic gain curves as a function of sodium peak conductance and voltage sensitivity of sodium activation curve.

A and B For each pair of voltage sensitivity and sodium peak conductance, the dynamic gain curve was calculated at 5Hz and 1Hz firing rates working points. CV values were fixed at 1.1 ± 0.05. C and D The dynamic gain curves were calculated at 5Hz and 1Hz firing rate with std of stimuli fixed at 0.04nA and 0.03nA. Correlation time of background current was 50ms. x_Na fixed at 40μm. Sodium peak conductance ranged from $1{\overline{g}}_{\text{Na}}$ to $20{\overline{g}}_{\text{Na}}$. k_a ranged from 0.1 to 6mV. Conductance and sensitivity are represented on a logarithmic scale. Grey points represent calculated data, continuous surfaces are obtained by Voronoi interpolation to allow for a continuous color representation.