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. 2020 Nov;9(11):6652–6659. doi: 10.21037/tcr-20-516

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2020 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Immunohistochemical analysis of CEA expression in gastric and colon tissues. (A) control gastric mucosa; (B) low grade dysplasia; (C) intestinal type gastric cancer. (E) colon tissues preneoplastic lesions (hyperplastic polyps and sessile serrated polyps); (F) tubular adenoma; (G) colorectal adenocarcinoma samples. Magnification ×200. Two-way ANOVA followed by Bonferroni post test analysis of IHC score values of gastric (D) and colon (H) cancer samples at different stages of disease. **, P<0.01, ***, P<0.001 (Figure S1B). 0–1= negative/borderline; 1= weakly expressed; 2 = expressed; 3= strongly positive. CEA, carcinoembryonic antigen.