Table 1. All 208 commonly differentially expressed genes (DEGs) were detected from two profile datasets, including 130 downregulated genes and 78 up-regulated genes in the CRC tissues compared to normal CRC tissues.

DEGs	Genes name
Upregulated	CDH3, SLCO4A1, IQGAP3, TPX2, MMP7, TRIB3, SERPINB5, CCNB1, FOXQ1, MMP3, ASPM, KRT80, LY6G6D, CDCA3, TCN1, ANLN, SLC7A5, CXCL2, CCNB2, PRC1, CDK1, PSAT1, PUS7, NFE2L3, CEP55, CEMIP, TOP2A, CLDN2, VSNL1, PHLDA1, CXCL1, SAPCD2, TMEM97, MCM4, CXCL8, AURKA, SLC12A2, REG1A, MAD2L1, DLGAP5, DPEP1, SOX9, HOXB8, PAICS, HMMR, REG1B, ASCL2, SCD, ETV4, PARPBP, CLDN1, STC2, CDCA7, COL11A1, CDC20, CENPN, CTHRC1UHRF1, ITGA2, KIAA0101, TESC, MYC, CCNA2, TTK, CDKN3, NME1, BUB1, NCAPG, TRIP13, MMP1, PTTG1, CDCA5, GINS2, UBE2T, CENPF, NUSAP1, CKS2, ESM1
Downregulated	PNCK, SPEG, LGALS2, HSPB6, FGL2, OTOP2, DPT, HSPB8, CCL23, MFAP4, ZG16, GUCA2B, WSCD1, CHP2, LRRN2, SCARA5, CLCA4, TCEAL2, ATP1A2, MYOM1, FAM129A, AKR1B10, MT1E, TUBAL3, PRKCB, CA4, CNN1, SEPP1, SDPR, CTSG, TRPM6, NXPE4, ADAMDEC1, ACKR1PY, CCL19, MYLK, HAND1, SLCO2A1, TMIGD1, DNASE1L3, CRYAB, SCIN, CKB, SLC26A3, CD36, CXCL12, PDE5A, MRGPRF, VIP, CA2, FLNC, CHGA, CLEC3B, MT1M, PKIB, ANPEP, ADH1A, CEACAM7, METTL7A, FHL1, ADTRP, PRPH, ST6GALNAC6, MT1G, CCL21, ABCA8, PDE9A, LMO3, TNFRSF13B, ACTG2, MT1F, KRT24, SLC16A9, BEST2, MYL9, INSL5, SLC51B, AQP8, ZBTB16, KCNMB1, DES, FABP4, TNFRSF17, NPTX1, SCGN, CLDN8, MS4A12, FAM107A, PLAC9, MYH11, PGM5, GPX3, SLC25A34, VSIG2, RNF150, NPY, ABI3BP, CALD1, GCNT2, SCNN1B, CASQ2, C2orf88, EPB41L3, CDKN2B, LAMA1, MAMDC2, RBPMS2, BEST4, CA1, SYNM, C7, TEX11, SLC4A4, C2orf40, SFRP1, PDK4, GFRA2, CFD, TMEM37, GPAT3, CPED1, RERGL, CHAIN, SLC51A, GUCA2A, SEMA6A, DHRS9, CA7, AFF3