Figure 5.
Cells apoptosis in A549 cells after transfections. After transfections, cells apoptosis rate at 72 h was increased in circ-ITCH(+) group compared with NC(+) group (A), and decreased in circ-ITCH(−) compared with NC(−) group (B). T-test was used to compare the rates of cells apoptosis in NC(+), circ-ITCH(+), NC(−) and circ-ITCH(−) between two groups. **, P<0.01. Circ-ITCH, circular RNA-itchy E3 ubiquitin protein ligase.