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. 2019 Apr;8(2):357–366. doi: 10.21037/tcr.2018.11.15

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2019 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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After A375.S2 cells were treated with inhibitors and Rg3 and the cell viability was analyzed by an MTT assay, it was found that the MEK inhibitor-treated group had a significant difference in cell viability compared to the Rg3 treated group without an inhibitor (P<0.05). MTT, methyl thiazol tetrazolium; PD, MEK inhibitor; SB, p38 MAPK inhibitor; SP, JNK MAPK inhibitor.