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. 2021 Mar;10(3):1509–1518. doi: 10.21037/tcr-21-375

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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MRI and pathological features of atypical meningiomas in clinical case 3. Male patient, 70 years old. (A) MRI shows a huge tumor with rich blood supply in the right temporal lobe, which has invaded the lateral wall of the right orbit causing sphenoid bone damage, and invasion of the infratemporal fossa, pterygopalatine fossa, and medial pterygoid and lateral pterygoid muscles outside the cranium. (B) HE staining (×100) shows tumor cells are arranged in small sheets, of papillary or whirlpool shape, with obvious nucleoli and abundant cytoplasm; Immunohistochemistry results show EMA (+/−), Vimentin (+), S100 (−), GFAP (−). MRI, magnetic resonance imaging; HE, hematoxylin-eosin; EMA, epithelial membrane antigen; S-100: S-100 protein; GFAP, glial fibrillary acidic protein.