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. 2020 Feb;9(2):603–612. doi: 10.21037/tcr.2019.11.56

Table 2. Correlation between SRC-1 or Twist1 level and clinicopathologic parameters.

Variables Case SRC-1 expression Twist1 expression
Positive Negative P Positive Negative P
Age
   >50 44 26 18 0.668 27 17 0.318
   ≤50 26 14 12 19 7
Tumor stage
   pT1/2, ≤5 cm 39 16 23 0.00224* 21 18 0.0409*
   pT3/4, >5 cm 31 24 7 24 7
Grade
   I/II 33 12 21 0.00037* 15 18 0.00074*
   III/IV 37 29 8 31 6
Gender
   Male 64 37 27 0.711 44 20 0.082
   Female 6 3 3 2 4
HBV
   Positive 59 36 23 0.321 40 19 0.275
   Negative 10 4 6 5 5
   Unknow 1 1 0 0 1
AFP (ng/mL)
   ≤400 31 18 13 0.890 20 11 0.852
   >400 39 22 17 26 13
   Unknow 0 0 0 0 0
Liver cirrhosis
   Yes 53 36 17 0.0013* 39 14 0.0143*
   No 17 4 13 7 10

*, statistically significant. HBV, hepatitis B virus; AFP, alpha-fetoprotein.