Table 2. Correlation between SRC-1 or Twist1 level and clinicopathologic parameters.
| Variables | Case | SRC-1 expression | Twist1 expression | |||||
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | P | Positive | Negative | P | |||
| Age | ||||||||
| >50 | 44 | 26 | 18 | 0.668 | 27 | 17 | 0.318 | |
| ≤50 | 26 | 14 | 12 | 19 | 7 | |||
| Tumor stage | ||||||||
| pT1/2, ≤5 cm | 39 | 16 | 23 | 0.00224* | 21 | 18 | 0.0409* | |
| pT3/4, >5 cm | 31 | 24 | 7 | 24 | 7 | |||
| Grade | ||||||||
| I/II | 33 | 12 | 21 | 0.00037* | 15 | 18 | 0.00074* | |
| III/IV | 37 | 29 | 8 | 31 | 6 | |||
| Gender | ||||||||
| Male | 64 | 37 | 27 | 0.711 | 44 | 20 | 0.082 | |
| Female | 6 | 3 | 3 | 2 | 4 | |||
| HBV | ||||||||
| Positive | 59 | 36 | 23 | 0.321 | 40 | 19 | 0.275 | |
| Negative | 10 | 4 | 6 | 5 | 5 | |||
| Unknow | 1 | 1 | 0 | 0 | 1 | |||
| AFP (ng/mL) | ||||||||
| ≤400 | 31 | 18 | 13 | 0.890 | 20 | 11 | 0.852 | |
| >400 | 39 | 22 | 17 | 26 | 13 | |||
| Unknow | 0 | 0 | 0 | 0 | 0 | |||
| Liver cirrhosis | ||||||||
| Yes | 53 | 36 | 17 | 0.0013* | 39 | 14 | 0.0143* | |
| No | 17 | 4 | 13 | 7 | 10 | |||
*, statistically significant. HBV, hepatitis B virus; AFP, alpha-fetoprotein.