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. 2020 Jun;9(6):3946–3959. doi: 10.21037/tcr-20-2147

Figure 4.

Figure 4

LncRNA FENDRR overexpression inhibited cell growth and aggressiveness in non-small cell lung cancer (NSCLC) cells in vitro. (A) FENDRR expression levels in 4 human lung cancer cell lines (A549, H1299, H460, H358) were measured by quantitative RT-PCR; (B) the quantitative RT-PCR assays quantified FENDRR level in H1299 cell with stable FENDRR over-expression; (C) FENDRR overexpression inhibited cell clonogenicity compared with the control transfectants in H1299 cell lines; (D) FENDRR overexpression led to cell growth arrest according to CCK8 assay compared with the control transfectants in H1299 cell lines; (E) Transwell migration assays in stable pWPXL-FENDRR H1299 cells and control; (F) Transwell invasion assays in stable pWPXL-FENDRR H1299 cells and control. The data are representative of 3 independent experiments. Values represent the mean ± SEM. ***, P<0.001 by Student’s t-test. The images in C were scanned and not enlarged. The images in E and F was magnified 100 times.