Table 2. The Cox proportional hazard model of CXC chemokines and six immune cells in hepatocellular carcinoma (TIMER).
Factor | coef | HR | 95% CI_low | 95% CI_up | P value | sig |
---|---|---|---|---|---|---|
B cell | −9.198 | 0.000 | 0.000 | 0.146 | 0.013 | * |
CD8_Tcell | −5.388 | 0.005 | 0.000 | 1.095 | 0.054 | |
CD4_Tcell | −3.968 | 0.019 | 0.000 | 15.100 | 0.245 | |
Macrophage | 7.093 | 1,203.394 | 5.072 | 285,492.940 | 0.011 | * |
Neutrophil | −4.923 | 0.007 | 0.000 | 5,375.505 | 0.475 | |
Dendritic | 6.610 | 742.556 | 16.357 | 33,710.562 | 0.001 | ** |
CXCL1 | 0.130 | 1.139 | 0.928 | 1.397 | 0.213 | |
CXCL2 | −0.226 | 0.798 | 0.699 | 0.911 | 0.001 | ** |
CXCL3 | −0.393 | 0.675 | 0.434 | 1.050 | 0.081 | |
PF4 | −0.058 | 0.944 | 0.631 | 1.412 | 0.778 | |
CXCL5 | 0.068 | 1.071 | 0.880 | 1.302 | 0.493 | |
CXCL6 | −0.219 | 0.803 | 0.676 | 0.954 | 0.013 | * |
PPBP | −0.095 | 0.909 | 0.484 | 1.710 | 0.768 | |
IL8 | 0.292 | 1.340 | 1.126 | 1.594 | 0.001 | ** |
CXCL9 | −0.174 | 0.840 | 0.671 | 1.051 | 0.127 | |
CXCL10 | −0.002 | 0.998 | 0.797 | 1.249 | 0.984 | |
CXCL11 | 0.039 | 1.040 | 0.758 | 1.427 | 0.810 | |
CXCL12 | −0.173 | 0.841 | 0.725 | 0.975 | 0.022 | * |
CXCL13 | 0.080 | 1.083 | 0.960 | 1.223 | 0.195 | |
CXCL14 | −0.003 | 0.997 | 0.822 | 1.210 | 0.978 | |
CXCL16 | −0.058 | 0.943 | 0.790 | 1.126 | 0.517 | |
CXCL17 | 0.142 | 1.153 | 0.994 | 1.336 | 0.059 |
*P<0.05, **P<0.01.