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. 2021 May;10(5):2399–2408. doi: 10.21037/tcr-21-749

Table 1. Molecular function enrichment analysis of DEGs (FDR <0.05 and |logFC| ≥1) bewtween normal and breast cancer tissues.

ID Description P.adjust qvalue Count
GO:0007059 Chromosome segregation 2.40E–09 2.20E–09 26
GO:0000070 Mitotic sister chromatid segregation 1.02E–08 9.30E–09 18
GO:0000819 Sister chromatid segregation 1.30E–07 1.19E–07 18
GO:0140014 Mitotic nuclear division 3.52E–07 3.22E–07 21
GO:0098813 Nuclear chromosome segregation 4.73E–07 4.33E–07 20
GO:0000280 Nuclear division 3.47E–06 3.17E–06 24
GO:0051983 Regulation of chromosome segregation 1.82E–05 1.66E–05 12
GO:0048285 Organelle fission 1.82E–05 1.66E–05 24
GO:0031581 Hemidesmosome assembly 0.000169 0.000155 5
GO:0043062 Extracellular structure organization 0.000169 0.000155 22
GO:0060337 Type I interferon signaling pathway 0.000704 0.000644 10
GO:0071357 Cellular response to type I interferon 0.000704 0.000644 10
GO:0030198 Extracellular matrix organization 0.000787 0.00072 19
GO:0034340 Response to type I interferon 0.000895 0.00082 10
GO:0008608 Attachment of spindle microtubules to kinetochore 0.001476 0.001352 6
GO:0007088 Regulation of mitotic nuclear division 0.001536 0.001406 12
GO:0000226 Microtubule cytoskeleton organization 0.001666 0.001526 22
GO:0050000 Chromosome localization 0.004205 0.00385 8
GO:0051303 Establishment of chromosome localization 0.004205 0.00385 8
GO:0030574 Collagen catabolic process 0.004654 0.004261 6
GO:0051783 Regulation of nuclear division 0.004654 0.004261 12
GO:0051310 Metaphase plate congression 0.004851 0.004442 7
GO:0006936 Muscle contraction 0.008553 0.007832 17

DEG, differentially expressed gene; FDR, false discovery rate.