Table 1. Molecular function enrichment analysis of DEGs (FDR <0.05 and |logFC| ≥1) bewtween normal and breast cancer tissues.
ID | Description | P.adjust | qvalue | Count |
---|---|---|---|---|
GO:0007059 | Chromosome segregation | 2.40E–09 | 2.20E–09 | 26 |
GO:0000070 | Mitotic sister chromatid segregation | 1.02E–08 | 9.30E–09 | 18 |
GO:0000819 | Sister chromatid segregation | 1.30E–07 | 1.19E–07 | 18 |
GO:0140014 | Mitotic nuclear division | 3.52E–07 | 3.22E–07 | 21 |
GO:0098813 | Nuclear chromosome segregation | 4.73E–07 | 4.33E–07 | 20 |
GO:0000280 | Nuclear division | 3.47E–06 | 3.17E–06 | 24 |
GO:0051983 | Regulation of chromosome segregation | 1.82E–05 | 1.66E–05 | 12 |
GO:0048285 | Organelle fission | 1.82E–05 | 1.66E–05 | 24 |
GO:0031581 | Hemidesmosome assembly | 0.000169 | 0.000155 | 5 |
GO:0043062 | Extracellular structure organization | 0.000169 | 0.000155 | 22 |
GO:0060337 | Type I interferon signaling pathway | 0.000704 | 0.000644 | 10 |
GO:0071357 | Cellular response to type I interferon | 0.000704 | 0.000644 | 10 |
GO:0030198 | Extracellular matrix organization | 0.000787 | 0.00072 | 19 |
GO:0034340 | Response to type I interferon | 0.000895 | 0.00082 | 10 |
GO:0008608 | Attachment of spindle microtubules to kinetochore | 0.001476 | 0.001352 | 6 |
GO:0007088 | Regulation of mitotic nuclear division | 0.001536 | 0.001406 | 12 |
GO:0000226 | Microtubule cytoskeleton organization | 0.001666 | 0.001526 | 22 |
GO:0050000 | Chromosome localization | 0.004205 | 0.00385 | 8 |
GO:0051303 | Establishment of chromosome localization | 0.004205 | 0.00385 | 8 |
GO:0030574 | Collagen catabolic process | 0.004654 | 0.004261 | 6 |
GO:0051783 | Regulation of nuclear division | 0.004654 | 0.004261 | 12 |
GO:0051310 | Metaphase plate congression | 0.004851 | 0.004442 | 7 |
GO:0006936 | Muscle contraction | 0.008553 | 0.007832 | 17 |
DEG, differentially expressed gene; FDR, false discovery rate.