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. 2021 Sep;10(9):3993–4001. doi: 10.21037/tcr-21-561

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Immune subtypes, stage, and immune score in KIRC. (A) Association of PD-1 and CTLA-4 gene expression with immune subtypes in KIRC. (B) Association of PD-1 and CTLA-4 gene expression with stage in KIRC. (C) The relationship between the expression of PD-1 and CTLA-4 and RNAss, DNAss, stromal score, immune score and ESTIMATE score was investigated using Spearman’s correlation test. **, P<0.01; ***, P<0.001. KIRC, kidney renal clear cell carcinoma; PD-1, programmed death-1; CTLA-4, cytotoxic T lymphocyte-associated protein-4.