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. 2019 Aug;8(4):1319–1325. doi: 10.21037/tcr.2019.07.30

Table 1. The production of cytokines of activated CD8+ cytotoxic T cells cultured in the presence or absence of IL-35 (pg/mL).

Cytokines PBS CD8+T CD8+T + IL-35 t P
IL-1β 0.021±0.002 3.678±0.541 2.730±0.173 −2.220 0.037
IL-6 0.031±0.004 25.337±7.113 11.687±1.598 1.872 0.077
IL-10 0.013±0.001 25.193±6.271 7.143±1.508 1.633 0.117
IL-12p70 0.041±0.003 1357.776±200.494 1006.806±64.37 −2.220 0.037
IFN-γ 0.022±0.002 230.796±52.678 117.833±60.951 1.147 0.264
IL-4 0.009±0.001 16.324±3.477 16.204±2.197 −0.051 0.962
TNF-α 0.016±0.002 33.324±4.17 31.537±5.011 −0.475 0.660