Table 4.
Describing normal glycemic thresholds
| Glucose level | Response | Effects | Role in the correction of hypoglycemia |
|---|---|---|---|
| 80-85 mg/dl | Decreased insulin | Increased lipolysis, increase fatty acid | 1st defense against hypoglycemia |
| 65-70 mg/dl | Increased Glucagon | Increased glucose production | 2nd defense against hypoglycemia |
| 65-70 mg/dl | Increased Epinephrine | Increased lipolysis, Increased free fatty acid | 3rd defense, critical when glucagon is deficient |
| 65-70 mg/dl | Increased Cortisol and growth hormone | Increased glucose production Decreased glucose clearance |
Involved in defense against prolonged hypoglycemia |
| 50-55 mg/dl | Symptoms | Recognition of hypoglycemia | Behavioral defense (food ingestion) |
| < 50 mg/dl | Decreased cognition | - | Compromises behavioral defense against hypoglycemia |