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. 2022 Winter;13(1):29–37. doi: 10.22088/cjim.13.1.29

Table 4.

Describing normal glycemic thresholds

Glucose level Response Effects Role in the correction of hypoglycemia
80-85 mg/dl Decreased insulin Increased lipolysis, increase fatty acid 1st defense against hypoglycemia
65-70 mg/dl Increased Glucagon Increased glucose production 2nd defense against hypoglycemia
65-70 mg/dl Increased Epinephrine Increased lipolysis, Increased free fatty acid 3rd defense, critical when glucagon is deficient
65-70 mg/dl Increased Cortisol and growth hormone Increased glucose production
Decreased glucose clearance
Involved in defense against prolonged hypoglycemia
50-55 mg/dl Symptoms Recognition of hypoglycemia Behavioral defense (food ingestion)
< 50 mg/dl Decreased cognition - Compromises behavioral defense against hypoglycemia