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. 2021 May;10(5):2470–2477. doi: 10.21037/tcr-21-724

Table 2. Relationship between the expression of Nanog and Fn14 and the pathological parameters of patients with NSCLC.

Pathological parameter Subgroups Case (n=89) Nanog expression, n (%) χ2 P Fn14 expression, n (%) χ2 P
Positive (n=61) Negative (n=28) Positive (n=52) Negative (n=37)
Gender Male 47 30 (49.18) 17 (60.71) 1.024 0.311 25 (48.08) 22 (59.46) 1.124 0.289
Female 42 31 (50.82) 11 (39.29) 27 (51.92) 15 (40.54)
Age (year) <60 39 25 (40.98) 14 (50.00) 0.007 0.934 22 (42.31) 17 (45.95) 0.116 0.733
≥60 50 36 (59.02) 14 (50.00) 30 (57.69) 20 (54.05)
Diameter of tumor (cm) >5 44 31 (50.82) 12 (42.86) 0.487 0.485 27 (51.92) 17 (45.94) 0.309 0.578
≤5 45 30 (49.48) 16 (57.14) 25 (48.08) 20 (54.05)
Differentiated degree Low 37 30 (49.48) 7 (25.00) 4.620 0.032 31 (59.62) 6 (16.22) 16.763 <0.001
Moderate/high 52 31 (50.82) 21 (75.00) 21 (40.38) 31 (83.78)
TNM stage I–II 35 18 (29.51) 17 (60.71) 7.832 0.005 8 (15.38) 27 (72.97) 30.047 <0.001
III–IV 54 43 (70.49) 11 (39.29) 44 (54.61) 10 (27.03)
Lymphatic metastasis Yes 50 41 (67.21) 9 (32.14) 9.588 0.002 39 (75.00) 11 (29.73) 17.996 <0.001
No 39 20 (32.79) 19 (67.86) 13 (25.00) 26 (70.27)
Histological type Adenocarcinoma 42 29 (47.54) 13 (46.43) 0.010 0.922 26 (50.00) 16 (43.24) 0.396 0.529
Squamous carcinoma 47 32 (52.46) 15 (53.57) 26 (50.00) 21 (56.76)

NSCLC, non-small cell lung cancer.