Table 2. Relationship between the expression of Nanog and Fn14 and the pathological parameters of patients with NSCLC.
Pathological parameter | Subgroups | Case (n=89) | Nanog expression, n (%) | χ2 | P | Fn14 expression, n (%) | χ2 | P | ||
---|---|---|---|---|---|---|---|---|---|---|
Positive (n=61) | Negative (n=28) | Positive (n=52) | Negative (n=37) | |||||||
Gender | Male | 47 | 30 (49.18) | 17 (60.71) | 1.024 | 0.311 | 25 (48.08) | 22 (59.46) | 1.124 | 0.289 |
Female | 42 | 31 (50.82) | 11 (39.29) | 27 (51.92) | 15 (40.54) | |||||
Age (year) | <60 | 39 | 25 (40.98) | 14 (50.00) | 0.007 | 0.934 | 22 (42.31) | 17 (45.95) | 0.116 | 0.733 |
≥60 | 50 | 36 (59.02) | 14 (50.00) | 30 (57.69) | 20 (54.05) | |||||
Diameter of tumor (cm) | >5 | 44 | 31 (50.82) | 12 (42.86) | 0.487 | 0.485 | 27 (51.92) | 17 (45.94) | 0.309 | 0.578 |
≤5 | 45 | 30 (49.48) | 16 (57.14) | 25 (48.08) | 20 (54.05) | |||||
Differentiated degree | Low | 37 | 30 (49.48) | 7 (25.00) | 4.620 | 0.032 | 31 (59.62) | 6 (16.22) | 16.763 | <0.001 |
Moderate/high | 52 | 31 (50.82) | 21 (75.00) | 21 (40.38) | 31 (83.78) | |||||
TNM stage | I–II | 35 | 18 (29.51) | 17 (60.71) | 7.832 | 0.005 | 8 (15.38) | 27 (72.97) | 30.047 | <0.001 |
III–IV | 54 | 43 (70.49) | 11 (39.29) | 44 (54.61) | 10 (27.03) | |||||
Lymphatic metastasis | Yes | 50 | 41 (67.21) | 9 (32.14) | 9.588 | 0.002 | 39 (75.00) | 11 (29.73) | 17.996 | <0.001 |
No | 39 | 20 (32.79) | 19 (67.86) | 13 (25.00) | 26 (70.27) | |||||
Histological type | Adenocarcinoma | 42 | 29 (47.54) | 13 (46.43) | 0.010 | 0.922 | 26 (50.00) | 16 (43.24) | 0.396 | 0.529 |
Squamous carcinoma | 47 | 32 (52.46) | 15 (53.57) | 26 (50.00) | 21 (56.76) |
NSCLC, non-small cell lung cancer.