Table 2. The relationship between clinicopathological factors and distant metastasis in male breast cancer.
| Characteristics | M0 (n=2,723), n (%) | M1 (n=250), n (%) | P value |
|---|---|---|---|
| Age at diagnosis (year) | 67.66±12.352 | 64.39±12.709 | <0.001* |
| <55 years | 445 (16.3) | 52 (20.8) | |
| ≥55 years | 2,278 (83.7) | 198 (79.2) | |
| Race | 0.008* | ||
| White | 2,219 (81.5) | 180 (72.0) | |
| Black | 373 (13.7) | 56 (22.4) | |
| Other | 131 (4.8) | 14 (5.6) | |
| Laterality | 0.019* | ||
| Right | 1,257 (46.2) | 105 (42.0) | |
| Left | 1,441 (52.9) | 130 (52.0) | |
| Bilateral | 25 (0.9) | 15 (6.0) | |
| T stage | <0.001* | ||
| T1 | 1,386 (50.9) | 21 (10.7) | |
| T2 | 1,096 (40.2) | 76 (38.8) | |
| T3 | 68 (2.5) | 24 (12.2) | |
| T4 | 173 (6.4) | 75 (38.3) | |
| N stage | <0.001* | ||
| N0 | 1,663 (61.1) | 65 (28.9) | |
| N1 | 756 (27.8) | 102 (45.3) | |
| N2 | 199 (7.3) | 29 (12.9) | |
| N3 | 105 (3.9) | 29 (12.9) | |
| Grade | <0.001* | ||
| I | 526 (19.3) | 10 (5.3) | |
| II | 1,345 (49.4) | 83 (44.4) | |
| III | 848 (31.1) | 90 (48.1) | |
| IV | 4 (0.1) | 4 (2.1) | |
| ER status | <0.001* | ||
| Positive | 2,656 (97.5) | 190 (86.0) | |
| Negative | 67 (2.5) | 31 (14.0) | |
| PR status | <0.001* | ||
| Positive | 2,497 (91.7) | 169 (76.1) | |
| Negative | 226 (8.3) | 53 (23.9) | |
| Her2 status | 0.005* | ||
| Positive | 585 (21.5) | 42 (20.1) | |
| Negative | 2,138 (78.5) | 167 (79.9) | |
| Subtypes | <0.001* | ||
| Her2−/HR+ | 2,403 (88.2) | 145 (70.0) | |
| Her2+/HR+ | 265 (9.7) | 35 (16.9) | |
| Her2+/HR− | 21 (0.8) | 7 (3.4) | |
| Triple negative | 34 (1.2) | 20 (9.7) |
*, represent the P value <0.05.