Table 3. The cellular components with enriched up-regulated or down-regulated genes.

Expression	Term	Count	P value	Benjamin
Up-regulation	Plasma membrane	179	3.2E−7	1.2E−4
	Extracellular space	75	8.1E−7	1.5E−4
	Extracellular region	84	2.1E−6	2.5E−4
	Basement membrane	13	5.1E−6	4.6E−4
	Cell surface	36	3.3E−5	2.4E−3
Down-regulation	Extracellular exosome	83	5.4E−5	1.4E−2
	Bicellular tight junction	11	6.6E−5	8.7E−3
	Plasma membrane	109	2.3E−4	1.5E−2
	Integral component plasma membrane	44	2.0E−4	9.8E−3
	Extracellular space	41	4.2E−3	1.5E−1