Table 3. Multivariate analysis of prognostic factors affecting overall survival.
| Variables | Overall survival, HR (95% CI) | P value |
|---|---|---|
| BCL2 and MYCa | 0.001* | |
| BCL2low and MYClow | 1.0 | |
| BCL2high and/or MYChigh | 5.63 (2.01–15.79) | |
| Body mass index, kg/m2 | 0.352 | |
| <27 | 1.0 | |
| ≥27 | 1.65 (0.58–4.73) | |
| NCCN-IPIb risk | 0.034* | |
| Low or low-intermediate | 1.0 | |
| High-intermediate or high | 3.11 (1.09–8.84) |
a, MYC expression: low: positive stain in <40% of cells; high: positive stain in ≥40% of cells; a, BCL2 expression: low: positive stain in <50% of cells; high: positive stain in ≥50% of cells; b, NCCN-IPI: National Comprehensive Cancer Network International Prognostic Index. *, P value with significance. HR, hazard ratio; CI, confidence interval.