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. 2021 Jan;10(1):57–64. doi: 10.21037/tcr-20-2370

Table 1. Clinical and pathologic characteristics of the CRC cases with MET and miR-133b mRNA expression.

Clinicopathological features Number miR-133b MET
Lowa (n=23) Higha (n=23) P value Lowa (n=23) Higha (n=23) P value
Age (years) 46
   ≥60 34 15 19 0.397 20 14 0.318
   <60 12 7 5 9 3
Tumor siteb
   Right 13 7 6 0.528 4 9 0.178
   Left 7 2 5 3 4
   Rectum 26 13 13 16 10
Tumor differentiation
   Well 2 0 2 0.138 1 1 0.712
   Moderate 28 11 17 12 16
   Poor 16 10 6 5 11
Staging
   I 6 3 3 0.432 4 2 0.677
   II 11 6 5 7 4
   III 25 19 6 12 13
   IV 4 4 0 0 4
Lymph node
   N0 18 5 13 0.028b 10 8 0.032b
   N1 21 8 13 17 4
   N2 7 6 1 2 5
Distant metastasis
   M0 42 17 25 0.022b 31 11 0.003b
   M1 4 4 0 0 4

a, low and high expression groups were determined by the median value of MET and miR-133b mRNA in the tumor tissue specimens; b, statistical significance (P<0.05). CRC, colorectal cancer; MET, mesenchymal-epithelial transition factor.