Table 2. A univariate analysis of the risk factor for the development of anastomotic stricture after esophagectomy.
| Clinical features | Total | Without stricture | With stricture | P value |
|---|---|---|---|---|
| Patients | 702 | 640 | 62 | – |
| Age | 59.0 (54.0–65.0) | 59.0 (54.0–65.0) | 58.0 (51.7–63.0) | 0.177 |
| Gender (female/male) | 132/570 | 120/520 | 12/50 | 0.907 |
| BMI at diagnosis | 21.3 (19.6–23.3) | 21.3 (19.6–23.3) | 21.6 (19.5–23.5) | 0.734 |
| Smoking (no/yes) | 232/470 | 214/426 | 18/44 | 0.481 |
| Diabetes (no/yes) | 687/15 | 627/13 | 60/2 | 0.545 |
| Hypertension (no/yes) | 612/90 | 553/87 | 59/3 | 0.049* |
| Length of tumor | 3.8 (3.0–5.0) | 3.9 (3.0–5.0) | 3.7 (3.0–5.0) | 0.938 |
| T-stage (T0/T1/T2/T3/T4) | 13/102/122/343/122 | 11/92/109/313/115 | 2/10/13/30/7 | 0.597 |
| N-stage (N0/N1/N2/N3) | 396/172/100/34 | 354/161/93/32 | 42/11/7/2 | 0.308 |
| Histological grading (G1/G2/G3) | 383/296/23 | 342/276/22 | 41/20/1 | 0.148 |
| Surgical approach (McKeown/Sweet/Ivor-Lewis) | 58/567/77 | 47/521/72 | 11/46/5 | 0.016* |
| Anastomotic technique (s-HS/CS/d-HS/SM) | 22/163/308/209 | 15/144/276/205 | 7/19/32/4 | 0.000* |
| Anastomosis site (cervical/below arch/above arch) | 106/121/475 | 84/112/444 | 22/9/31 | 0.000* |
| Total number of removed lymph node (≥16/<16) | 332/370 | 294/346 | 38/24 | 0.021* |
| Anastomotic leakage (no/yes) | 667/35 | 612/28 | 55/7 | 0.017* |
*, P<0.05. Diagnostic criteria for diabetes: A fasting plasma glucose of ≥7.0 mmol/L, a 2-hour plasma glucose value in a 75 g oral glucose tolerance test of ≥11.1 mmol/L or a glycated hemoglobin (A1C) of ≥6.5%.