Figure 2.
IL-10 gene hypomethylation correlates with poor overall HCC survival. (A) Kaplan-Meier analysis of survival in HCC patients discriminated by IL-10 methylation index. Low IL-10 promoter methylation (MI <0.5) was significantly correlated with poor overall survival after surgery in HCC patients; (B) HCC patients with hypomethylated (∆MI ≤0) IL-10 showed poorer survival. ∆MI = MIHCC – MInon-tumor. IL-10, interleukin-10; HCC, hepatocellular carcinoma; MI, methylation index.