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. 2021 Nov;10(11):4664–4679. doi: 10.21037/tcr-21-1646

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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XPO1 expression in normal tissues, tumor tissues, and cancer cell lines. (A) Differential expression analysis of XPO1 in normal and tumor samples of 33 tumor types (*, P<0.05; ***, P<0.001. The P value of each tumor: BLCA: 5.61e-04; BRCA: 2.97e-09; CESC: 0.08; CHOL: 2.26e-09; COAD: 4.87e-16; ESCA: 1.2e-06; GBM: 0.013; HNSC: 7.85e-15; KICH: 6.58e-09; KIRC: 3.14e-08; KIRP: 2.35e-05; LIHC: 1.73e-20; LUAD: 2.22e-18; LUSC: 1.71e-25; PAAD: 0.966; PCPG: 0.265; PRAD: 0.852; READ: 0.02; SARC: 0.023; SKCM: 0.883; STAD: 1.27e-15; THCA: 7e-04; THYM: 0.251; UCEC: 0.98). (B) XPO1 expression in normal tissues (based on data from the GTEx database). (C) XPO1 expression in tumor cell lines (based on data from the CCLE database). XPO1, Exportin 1; BLCA, bladder carcinoma; BRCA, infiltrating ductal carcinoma; CHOL, cholangiocarcinoma; COAD, colon adenocarcinoma; ESCA, esophageal carcinoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; KICH, kidney chromophobe renal cell carcinoma; KIRC, kidney clear cell renal cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; PAAD, pancreatic adenocarcinoma; PCPG, pheochromocytoma/paraganglioma; PRAD, prostate adenocarcinoma; READ, rectum adenocarcinoma; SARC, sarcoma; SKCM, skin cutaneous melanoma; STAD, stomach adenocarcinoma; THCA, thyroid carcinoma; THYM, thymic carcinoma; UCEC, uterine corpus endometrial carcinoma.